Syllabus - 2008

     7 Apr 08

Context and History of GM

1/15
QUIZ
Introduction (ppt)

On these assignments, see note

- Charles 2001, Lords of the Harvest
- DeVries & Toenniessen on defining biotechnology (not the excerpt from p. 73)
- optional: Paarlberg & Pray 2007, Political Actors on the Landscape; Source Watch and entry on Ctr Cons Freedom


1/17 Current Events (ppt) (quiz results);
Future of Food video (note)
1/22 finish Future of Food; overview
1/24 History & overview of GM (ppt)
1/29 Social history of GM (ppt) - Stone 2002, "Both Sides Now" including online backgrounder (pdf file with separate backgrounder)

Biology of GM

1/31

 

B. Kunkel: genes & expression (ppt) - Chrispeels & Sadava, Molecular Basis of Genetic Modification (Chapter 6) (Eres)
- Recommended: Glick & Pasternak, DNA-RNA-Protein Synthesis (Eres)
2/5 E. Richards: how transformation works (pdf)
2/7 B. Kunkel: After transformation (ppt) - Chrispeels & Sadava, 20 on myths and facts related to safety of GM crops -- especially Myths 1, 6, 9, sections 20.3 and 20.4 -- but treat it more as an editorial than a scientific account (Eres)
- Recommended: Bach & Khan 2004 Taming Plastids, on chloroplast transformation

Theory and Politics of Designing Plants

2/12
quiz 1
"Tampering with nature" (ppt) Prince of Wales 1999, Questions about GMO's
2/12
7 pm
Formal breeding (ppt)

Kloppenburg 2005, First the Seed, chaps 1-2, or chaps 1-7, 10, 11 if this is your optional book. 

2/14 Commodification of agriculture (ppt)
2/19 Food quantity (ppt) - Borlaug 2000, Are We Going Mad?
- Sen 1981, chapter 1 from Poverty and Famine
- Optional: Sen 1993, Economics of Life & Death, pp. 40-42; Stone, Malthusianism
2/21

Food quality (ppt)

- Pollan 2007, Unhappy Meals
- Schlosser 2001, Food Product Design (from Fast Food Nation)
- NYT 2003, The Food Simulator

Gene Flow and the Politics of Studying It; GM and the Corporate University

2/26 B. Schaal: Biology of gene flow (ppt)

- skim: Quist & Chapela 2001, original paper (also as pdf )
- skim: Quist & Chapela 2002, follow-up including editorial note
- skim: Snow et al. 2003, Bt Transgene...
- skim: Ortiz-Garcia et al. 2005, Absence of detectable transgenes...

("skim" means get the main points but you are not responsible for technical details beyond what we discuss in class)

- optional: Snow 2003, Unnatural selection
- Can the "terminator" GURT spread? (Vandana thinks so...)

2/28

Scientific politics, public discourse, and university-industry relations (ppt)

Universities and Industry
- Etzkowitz & Leyesdorff 1997 Universities in the global knowledge economy excerpt

optional: Stein 2004, Buying In or Selling Out: The Commercialization of the American Research University

The Chapela Case
-
Caught in the maize at Berkeley
- optional: Chapela 2006 (Scandal reveals political greed)
- optional: Berkeley webcast on scientific dissent
- optional: index to articles on Chapela

Chapela Spin
- skim: Guardian 2002, Mexican govn findings and on Nature's handling of paper
- CBI 2002, industry view of the Nature paper
- Monbiot 2002, Fake Persuaders (including the CFFAR site & Smetacek petition)
- AP 2002, article on "corporate meddling in academia"
- optional: WP article on internet shills and meat puppets

Sunflowers Spin
- Nature story on blocking Snow's research
- Stewart 2003, Press Before Paper or pdf
- Nature summary of Stewart study or pdf
- optional: Syngenta and Hayes

3/4 David Cleveland: Transgenes, maize, and Mexican farmers (pdf)


- Soleri et al. 2006, Transgenic Crops and Crop Varietal Diversity: The Case of Maize in Mexico
- optional: Raven 2005, Transgenes in Mexican maize: desirability of inevitability?

Midterm and Break

3/6 Midterm exam 1 (whole course to date)
3/11-13 Break

International GMO's: Intellectual Property, WTO, and Biotech for the Poor

3/18 - 3/20

IP - domestic (ppt)

patents!

MIT Human Gene Patents
(to search on gene "Xa21", type "Xa21[sym]" in gene box)

 

- Sell 2003 (from US Int. Prop. Rights in Historical Perspective pp. 60-72)
- Golden 2001 ( Biotechnology, Technology Policy, and Patentability, pt I)
- Pringle 2003:85-93 (from Food Inc.)
- look at patent #5,352,605 at USPTO
Recommended:
- Noonan 2004 (When Words Fail)
- Stone 2005, A Science of the Gray, pp. 204-208

- Jensen & Murray 2005, Intellectual Property Landscape of the Human Genome
3/25

IP - international:
WTO and TRIPS (ppt)

- Crucible II Group 2000 (Seeding Solutions, pp. 86-108)
- Stock and Johnston 2001 on Battle in Seattle
Recommended
- WIRED: Geography of the Genome
- McMichael 2000, Global Food Politics (Eres)
- Lessig 2004, Taste of Our Own Poison
- Cohen 2005, Poorer nations turn to public GM crops

 

3/27
quiz 2

WTO and Europe

Biotech and the Third World

4/1 N. Taylor: biotech for Africa (pdf) - Taylor et al. 2004 (Development and application of transgenic technologies in cassava) -- see note
- Recommended: abstracts on increased starch (Ihemere et al. 2006) and virus resistance (Chellappan et al. 2004)
4/3

Road trip
1:07 sharp in front of Brookings

- peruse the DDPSC website and in particular read the mission statement; view the ILTAB page
4/8

Africa; China; South America

(ppt)

- DeVries and Toenniessen 2001 Securing the Harvest Chap 5
- BBC 2002, Food Crisis Worsens in Southern Africa
- Toronto Star 2002, Millions Dying (reposted on the CBI website)
- Greenpeace 2002, USAID and GM Food Aid (pdf)
- CS Monitor 2003 on the Zambian famine that wasn't
- Smale et al. 2006, Bales and Balances -- section on So. Africa
- Smale et al. 2006, Bales and Balances -- section on China
Recommended:
- Georgetown study: Genetically Modified Food in the Southern Africa Food Crisis of 2002-2003
- NYT 2004 on GM ban in Angola
- Wash Post 2003 on efforts to ease famine in Africa
4/10 India (ppt) - Stone 2002, Biotechnology and Suicide in India
- Leonard 2007, Ganesh and Brahma bow to a new god
Recommended:
- Stone 2007, Agricultural Deskilling and the Spread of Genetically Modified Cotton in Warangal
- Stone 2007, Birth and Death of Traditional Knowledge
- Stone 2005, A Science of the Gray: Malthus, Marx, and the Ethics of Studying Crop Biotechnology

Alternative Foods and Agricultures

4/15 Margaret Mellon: industrial beef (ppt)

-Martineau 2001, First Fruit pp. 60-109 (or all if this is your optional book ) (note)
- Eichenwald et al. 2001, Biotechnology Food: From the Lab to a Debacle
Recommended:
- Federal Register on Coordinated Framework (Vol 51, June 26, 1986,  just pp. 23302-23310.
- Federal Register on Food Policy (Vol 57, May 29, 1992,  pp. 22984-23005.)

4/17 Peggy Barlett: alternative foods and agricultures (ppt)  

Hey, we have to do it:

4/22

Final exam (cumulative but somewhat greater emphasis on material after the mini-midterm)